Committees and Organization of International Meningioma Consortium (ICOM)

Expert Pathology Committee:

Goals: The pathology committee provides expertise in review of slides to determine whether the tissue block (from which the slide originates) is qualified to make DNA/RNA; as well as expertise to ensure consistency in diagnostic criteria.

Members: Marta Couse, Kieren Allinson, Catarina Giannini, Bianca Pollo, Houtan Noushmehr, Felix Sahm

Clinical Annotation Committee:

Goals: Determine the minimal requirements of clinical annotation for samples analyzed through the consortium. Collect and standardize all clinical data to provide a unified set of clinical annotation for all cases in the cohort

Members: Jill Barnholtz-Sloan, Warren Selman, Ramez Kirollos, Thomas Santarius, Michael Jenkinson, Eva Galanis, Laila Poissonm, Andrea Saladino, Houtan Noushmehr, Francesco Dimeco,

Data Infrastructure and Processing Committee:

Goals: Identify the set of requirements for data storage and processing infrastructure; evaluate possible third party solutions including GenoSpace, BioFortis, and Synapse/SAGE. Determine the process for unified analysis of all existing data sets and provide support to all sites where the data processing pipeline needs to be implemented.

Members: Jill Barnholtz-Sloan, Alexis Joannides, Laila Poisson, Jim Snyder, Houtan Noushmehr, Matthias Futschik

Clinical Oncology and Translational Research Committee:

Goals: Organization of clinical studies that can be generated based on data collected within the consortium; identify existing or future translational projects related to delivery of radiation treatment or and additional therapeutic modalities for implementation in to relevant clinical trials.

Members: Patrick Wen, Warren Selman, Andrew Sloan, Priscilla Brastianos, Michael Jenkinson, Michael Vogelbaum, Helen Shih, Ian Lee, Jim Snyder, Daniel Lachance, Christian Schichor, Joerg-Christian Tonn, Roland Goldbrunner, Oliver Hannemann

Imaging and Therapeutic Response Assessment Committee:

Goals: Evaluate imaging modalities and response assessment in concert with retrospective and prospective studies to evaluate treatment efficacy and correlates of recurrence-free survival

Members: Patrick Wen, Priscilla Brastianos, Helen Shih, Joerg-Christian Tonn, Christian Schichor, Timothy Kaufmann, Jim Snyder, Roland Goldbrunner

Quality of Life, Patient Outcomes, Advocacy and Health Economics Committee:

Goals: Organization of clinical studies that can be generated based on data collected within the consortium

Members: Alexis Joannides, Thomas Santarius, Helen Shih, Karen Devine, Tobias Walbert, Ian Lee, Jim Snyder, Christian Schichor, Roland Goldbrunner

Ethics and Publications Committee:

Goals: Develop verbiage in support of IRB protocols. Establish policies pertaining to data ownership, publications, authorships.

Members: Thomas Santarius, Joerg-Christian Tonn, Houtan Noushmehr, Michael Jenkinson

Funding Committee:

Goals: Identify funding sources in support the consortium efforts. Provide support to participants aiming to submit grant proposals; develop verbiage and figures that could be used, collect and provide letters of support.

Members: Thomas Santarius, Houtan Noushmehr